Impaired Lymphocyte Reactivity Measured by Immune Function Testing in Untransplanted Patients with Cirrhosis
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چکیده
منابع مشابه
Impaired lymphocyte reactivity measured by immune function testing in untransplanted patients with cirrhosis.
The immune function test is an integrated measure of total mitogen-inducible CD4(+) T cell metabolic activity in the peripheral blood, and it is used to guide the dosing of immunosuppressive medications after solid organ transplantation. Recently, low CD4(+) T cell metabolic activity due to pharmacologic immunosuppression has been linked to rapidly progressive cirrhosis in hepatitis C virus (HC...
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The autologous mixed lymphocyte reaction (MLR) is severely impaired in patients with acute infectious mononucleosis. Reactivity returned during the course of convalescence. The allogeneic MLR was not impaired in these patients. B cells from patients with infectious mononucleosis do not stimulate autologous T-cell proliferation, and this observation appears to explain the cellular basis of the i...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2013
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cvi.00595-12